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PT-141 Bremelanotide Injection Anabolic Steroids 189691-06-3 10 mg/vial

PT-141 Bremelanotide Injection Anabolic Steroids 189691-06-3 10 mg/vial


PT-141 or Bremelanotide is the generic term for a research peptide being studied for its possible use in helping to improve sexual dysfunction in both men (erectile dysfunction or impotence) and women (sexual arousal disorder).

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PT-141 or Bremelanotide is the generic term for a research peptide being studied for its possible use in helping to improve sexual dysfunction in both men (erectile dysfunction or impotence) and women (sexual arousal disorder).

PT-141 was developed from the tanning peptide Melanotan 2, which is a synthetically produced variant of a peptide hormone naturally produced in the body that stimulates melanogenesis that is known as alpha-Melanocyte stimulating hormone. MSH, activates certain melanocortin receptors in the process of exerting its effects. Indeed, MSH also exerts potent influence over lipid metabolism, appetite, and sexual libido. Resultantly, PT-141 has been shown in studies to exhibit libido-enhancing effects by activating the melanocortin receptors MC1R and MC4R, but not skin tanning.

 

Melanotan 1 and Melanotan 2 have been researched for their use in protecting against the harmful effects of ultraviolet radiation from sunlight due to their melanogenesis-stimulating properties.

 

 

PT-141 and Sexual Dysfunction

 

PT-141 is a potential remedy for the treatment of sexual dysfunction; specifically, male erectile dysfunction. Studies have shown that PT-141 does not act on the vascular system like former compounds, but allegedly works by activating melanocortin receptors in the brain, therefore helping increase ones sexual stimulation.

 

PT-141 is a melanocortin based peptide that has shown effectiveness in clinical studies on both male and female rats. Male rats have shown erectile response with doses as low as 1-2 mgs whereas most female rats have shown positive results with higher doses around 2-3 mgs. While the dosage requirements tend to be higher for female rats, the observable results in female rats tend to be stronger.

 

 

PT-141 Bremelanotide

 

Sequence: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH

Molecular formula: C50H68N14O10
Molar Mass: 1025.2
CAS number: 189691-06-3
PubChem: CID 9941379
PT-141 Structural Names: cyclo-[Nle4, Asp5, D-Phe7, Lys10]alpha-MSH-(4-10)
PT-141 is a metabolite of Melanotan 2

The Development of PT-141

 

PT-141 was developed from the Melanotan 2 peptide, which underwent testing as a sunless tanning agent. In initial testing, Melanotan 2 did induce tanning, but additionally caused sexual arousal and spontaneous erections as unexpected side effects in nine out of the ten original male volunteer test subjects.

 

Palatin completed patient treatment in its Phase 2B clinical trial in premenopausal women with FSD Primary data analysis and announcement of top-line results anticipated in first-half of fourth quarter of calendar year 2012. In studies, PT-141 was shown to be effective in treating sexual dysfunction in both men (erectile dysfunction or impotence) and women (sexual arousal disorder). Unlike Viagra and other related medications, it does not act upon the vascular system, but directly increases sexual desire via the nervous system.
PT-141, bremelanotide is experimental and is used for the purpose of sexual arousal. It is a melanocortin based peptide that has shown effectiveness in clinical studies on both male and female rats. Male rats have shown erectile response with doses as low as 1-2 mgs whereas most female rats have shown positive results with higher doses around 2-3 mgs.

 

While the dosage requirements tend to be higher for female rats, the observable results in female rats tend to be stronger. An example of findings among male rats is displayed below in an abstract from this Palatin study:

 

Bremelanotide or PT-141 is the generic term for a new research peptide for use in helping improve sexual dysfunction in men (erectile dysfunction or impotence) as well as helping improve sexual dysfunction in women (sexual arousal disorder).


Bremelanotide, PT-141 does not act on the vascular system like the former compounds but it is known and has been shown to help increase sexual activity in both male and female mammals. Bremelanotide PT-141 allegedly works by activating melanocortin receptors in the brain, therefore helping increase ones sexual stimulation.

 

 

PT-141 (Bremelanotide) and questions

 

 

What is PT-141?


PT-141 is a libido peptide. It is used to treat sexual dysfunction in women as well as hemorrhagic shock, and reperfusion injury. It was available in a nasal spray until it was discontinued in 2008 after health concerns. It is now available as a substance to use for injection.

PT-141 came from the Melanotan testing that occurred in scientific studies. They noticed what while Melanotan and Melanotan II were successful in tanning skin without sunlight, the side effects were sexual arousal in men and women with erection benefits for men who had erectile dysfunction. In a third clinical trial, PT-141 was shown to enact the lordosis behavior in animal test subjects. It directly changes the chemicals in the brain that turn on during arousal without passing through the blood stream.

 

How much PT-141 should I take?


For humans the dosage they used in clinical trials was 0.75, 1.25, and 1.75 mg and each provided effective in helping with sexual stimulation of human test subjects.

 

What are the side effects of PT-141?


Some side effects include an increase in blood pressure, nausea, yawning, stretching, decreased appetite, transient facial flushing, sweating, somnolence, headache, dizziness, dysgeusia (altered sense of taste), hypertension, and skin hyper-pigmentation.

 

How should I store PT-141?


PT-141 comes as a powder so storing it in a cool dry place works best. But for injection it would be necessary to use bacterial prevention solutions so that the effectiveness is more potent than a water solution. If you plan to inject it would have to be on the spot prior to injection preparedness or it can be administered at a later time. Most studies do not have any information disclosing shot storage or usage.

 

 

 

PT 141 Bremelanotide Peptide

 

Synthetic Love

In terms of popularity, there is no doubt that peptides are making their way to the top, especially in the bodybuilding world, mainly due to their muscle building, healing and recovery properties.
 
One peptide that has been gaining a lot of exposure lately is PT-141, which has captured the attention of both the media and the public, resulting from studies investigating of its potentials on treating reperfusion injuries and shock from hemorrhages as well as in sexual dysfunction and low libido. [Interesting, isn’t it?
 
Maybe you are asking, “What really are the potent benefits that users get from it?” This may be your major question while in the middle of researching and deciding whether or not to go for PT141, and you’re exactly at the right place to find substantial data about it. Let’s begin.


What Is PT-141?

Used as an erectile dysfunction solution, it is used by men who want to bring back the fire into their sex life in terms of achieving rock-hard erections that do not only satisfy them but their partners as well. In the process, they never have to take any other medications or choose hormone replacement therapy again with it at their side.

The study that has proven its effects in terms of sexual dysfunction was performed on lab rats, wherein the male rats with erectile dysfunction were given this peptide and exhibited improvements in terms of sexual performance as compared to the controlled group, which was not given the research chemical.
Aside from male rats that benefitted from Bremelanotide, female rats, which have shown an increased sexual performance after therapy with the peptide, also did.

For humans, it is seen with potential benefits, too. Women who experience low libido due to aging that leads to hormonal imbalance can benefit from it that may give them hope for bringing back their sexual desire.


How PT-141 Works

It is believed that it can improve both male and female sexual problems by increasing their sexual performance and desire in lovemaking. This happens because it is discovered to stimulate mPOA terminals in the brain of rats.

This action led the research chemists into identifying it as a potent stimulator of that brain’s part, which can activate the dopamine hormones that happens to play a major role in sexual motivation.

What is dopamine? Known as a compound in the body, it functions as a neurotransmitter that stimulates performance. What happens with low levels of dopamine in the brain is that there will be low libido, which causes can be traced in the brain.

So by comparing those with low dopamine levels versus those with a healthy level, the latter is better in terms of getting into arousal and having desire, as facilitated by their brain’s neurotransmitters. Without even saying, people can treat low libido by addressing neurotransmitter issues and such include low levels of dopamine, serotonin and testosterone.

With PT141 peptide, you can address the problem on sexual dysfunction, whether you’re a man or a woman suffering from it, but that’s if you are going to consider using it for yourself.


Based on reviews, users find the peptide beneficial, resulting to high demands for it on the market. And apart from being a reliable treatment for lack of sexual desire and erectile dysfunction, it is also very affordable. In this case, even those on a budget can now afford treatment that can help them get rid of low libido. In fact, this very helpful peptide is for sale at low prices averaging $30, but it may vary from seller to seller.


Right now, couples use it together so that they can gauge its effects on their sex lives. Many of them are trying to figure out if it could increase their level of desire for each other and if it could improve their sex performance.


Today, raving reviews advocated by users themselves are online and almost all of them are in favor of this peptide. However, you may also want to take note that effects may vary from person to person, affected by factors, including bodily reactions.


Aside from higher libido and longer lasting erections, users are enjoying a more youthful energy that they never did before. They’re saying that this peptide has helped them achieve more energy, as if they were in their 20s.


In this case, not one of the thousands of users is planning to switch back to conventional sex-enhancing medications or treatments like Viagra or Cialis (for erectile dysfunction), which are only for men.
They don’t only appreciate how it can help them improve their sexual function, but they also love the high energy level that it gives them, helping them live a fuller life.


Overall, the general public consensus, when talking about PT-141, is highly positive. So if you’re interested improving your sex life and experience higher libido or harder and stronger erections that last long, then it may be time that you consider it for yourself.



Does It Have Side Effects?

There are no conclusive studies on it and many of them are in progress. This peptide isn’t also approved yet by the FDA. Right now, it is only available as a research chemical, which is for sale online. In this case, there are no noted significant side effects at the moment because many reviews are based on anecdotal reports of users themselves.


Many of these reviews can be found on discussion boards online. But while there are tons of user reviews online, none of these displayed or noted any negative feedbacks about the peptide.



How Is PT-141 Used?

It’s commonly injected, but some users opt for nasal atomizers, too. No matter which route you choose, however, you have to read and understand instructions on the label for the best results and for your safety, of course.


There are also PT-141 products available in powder form, which you will have to reconstitute in bacteriostatic water. Nevertheless, practice proper self-injection and disposal methods. If you’re new to it, ask the help of a doctor or a nurse on the proper way to self-inject.


You probably know by now the most essential data about it when deciding if it’s for you or not. Summing up, it is a promising peptide made to deliver you the results you’re looking for enhancing your sexual desire (women) or giving you longer-lasting and harder erections (men).


Bring back the fire into your intimate relationship, feel more alive and experience youthfulness like never before.

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